Association of the changes in pulmonary artery diameters with clinical outcomes in hospitalized patients with COVID-19 infection: A crosssectional study

Objective: Enlarged pulmonary artery diameter (PAD) can be associated with mortality risk in coronavirus disease 2019 (COVID-19) patients. Our aim is to find the factors that cause changes PAD and relationship between radiological findings clinical outcomes COVID-19 Patients Methods: In this descriptive, retrospective, single centered study, among hospitalized 3264 patients, 209 patients previous chest computed tomography (CT) were included. Findings of current CTs obtained during compared CTs. Pulmonary involvements, World Health Organization (WHO) Clinical Progression Scale scores laboratory variables recorded. Intensive Care Unit (ICU) admission, intubation evaluated by using uni – multivariate analyses. Results: high D-dimer had significantly increased for enlarged increase CT (ΔPAD) (OR=1.18, p<0.05, OR=1.2 p<0.05). Both an over 2 mm (ΔPAD 2mm) significant risks ICU intubation, (OR= 1.18 p<0.01, OR=1.22 OR=2.62 OR=2.12 OR=2.32 OR=2.09 p<0.001 respectively). It was found PAD, admission increased. (OR=3.03 p<0.001, OR=2.52 p<0.01). Combined age lymphocyte counts, predicted a 50% sensitivity, 88% specificity (AUC=0.83, p<0.001). Conclusion: PPatients severity, mortality. High levels CRP suggest inflammation thrombosis may effective pathogenesis.